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Index > Protein center > Edar(Gene name) > Mouse
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  • Edar (Gene name),
  • Tumor necrosis factor receptor superfamily member EDAR (Protein name ),  EDAR_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Edar(Dl);
    Protein name:
    Tumor necrosis factor receptor superfamily member EDAR;
    Alternative:
    Downless;Anhidrotic ectodysplasin receptor 1;Ectodysplasin-A receptor;Ectodermal dysplasia receptor;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds to EDARADD. Associates with TRAF1, TRAF2, TRAF3 and NIK.
    Function:
    Receptor for EDA isoform TAA, but not for EDA isoform TA-2 (By similarity). May mediate the activation of NF-kappa-B and JNK. May promote caspase-independent cell death.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    448
    Sequence:
    50:
    MAHVGDCKWM | SWLPVLVVSL | MCSAKAEDSN | CGENEYHNQT | TGLCQQCPPC | 
    100:
    RPGEEPYMSC | GYGTKDDDYG | CVPCPAEKFS | KGGYQICRRH | KDCEGFFRAT | 
    150:
    VLTPGDMEND | AECGPCLPGY | YMLENRPRNI | YGMVCYSCLL | APPNTKECVG | 
    200:
    ATSGVSAHSS | STSGGSTLSP | FQHAHKELSG | QGHLATALII | AMSTIFIMAI | 
    250:
    AIVLIIMFYI | MKTKPSAPAC | CSSPPGKSAE | APANTHEEKK | EAPDSVVTFP | 
    300:
    ENGEFQKLTA | TPTKTPKSEN | DASSENEQLL | SRSVDSDEEP | APDKQGSPEL | 
    350:
    CLLSLVHLAR | EKSVTSNKSA | GIQSRRKKIL | DVYANVCGVV | EGLSPTELPF | 
    400:
    DCLEKTSRML | SSTYNSEKAV | VKTWRHLAES | FGLKRDEIGG | MTDGMQLFDR | 
    448:
    ISTAGYSIPE | LLTKLVQIER | LDAVESLCAD | ILEWAGVVPP | ASPPPAAS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member EDAR
    Cat.:
    E15171h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Tumor necrosis factor receptor superfamily member EDAR
    Cat.:
    E15171m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member EDAR
    Cat.:
    U15171h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tumor necrosis factor receptor superfamily member EDAR
    Cat.:
    U15171m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member EDAR
    Cat.:
    P15171Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member EDAR
    Cat.:
    P15171Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member EDAR
    Monoclonal Antibody for Mouse Tumor necrosis factor receptor superfamily member EDAR
    Protein for Mouse Tumor necrosis factor receptor superfamily member EDAR
    Protein for Mouse Tumor necrosis factor receptor superfamily member EDAR

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Involvement of a novel Tnf receptor homologue in hair follicle induction."
      Headon D.J. , Overbeek P.A.
      Nat. Genet.22:370-374(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT LYS-379
      tissue: Embryonic foot.
      tissue: Embryonic skin.
      tissue: Embryonic tail.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 205-448
      strain: C57BL/6J.
      tissue: Lung.
    3. 3.
      "TNF signaling via the ligand-receptor pair ectodysplasin and edar controls the function of epithelial signaling centers and is regulated by Wnt and activin during tooth organogenesis."
      Laurikkala J. , Mikkola M.L. , Mustonen T. , Aaberg T. , Koppinen P. , Pispa J. , Nieminen P. , Galceran J. , Grosschedl R. , Thesleff I.
      Dev. Biol.229:443-455(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY ACTIVIN A
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